Urinary & Sexual Health

Chancroid: Symptoms, Causes, and Treatment via a UK Online Doctor

6 min readLast reviewed 11 October 2026

Educational information — not medical advice.

This article was prepared by the OnlineDoctor24 editorial team and reviewed for factual accuracy against UK clinical guidance (NHS and NICE). It is not written by a doctor and does not replace personal medical advice. For symptoms specific to you, book an online doctor consultation.

Key points

  • Chancroid is a bacterial sexually transmitted infection (STI) caused by Haemophilus ducreyi.
  • The primary symptom is the development of one or more painful, soft sores or ulcers on the genitals.
  • Swelling and pain in the lymph nodes of the groin (buboes) are common complications if left untreated.
  • It is distinct from syphilis and genital herpes, which often present with different types of sores.
  • Treatment usually involves a short course of targeted antibiotics such as azithromycin or ceftriaxone.
  • Confidential consultations with an online doctor can help differentiate these symptoms from other STIs.

What is Chancroid?

Chancroid is a bacterial infection that is primarily transmitted through sexual contact. It is caused by the Gram-negative bacterium Haemophilus ducreyi. While relatively rare in the United Kingdom compared to other STIs like chlamydia or gonorrhoea, it remains a significant concern for those who have recently travelled to areas where the infection is more prevalent, such as parts of Africa, Asia, and the Caribbean.

Unlike the 'hard chancre' associated with syphilis, the sores caused by chancroid are typically soft to the touch and significantly more painful. In the UK, sexual health clinicians look for specific clinical markers to diagnose this condition, often using NICE guidelines to differentiate it from other common causes of genital ulceration.

Recognising the Symptoms of Chancroid

Symptoms usually appear between four to ten days after exposure, though the incubation period can range from one to thirty-five days. The infection typically progresses through several stages:

  • Initial Bump: A small, red bump (papule) appears at the site of infection.
  • Ulcer Formation: Within a day or two, the bump becomes a painful, open sore filled with grey or yellowish fluid.
  • Painful Ulcers: The ulcers are 'soft' (unlike syphilis) and have ragged, irregular edges. They bleed easily if touched.
  • Swollen Groin Glands: In about half of all cases, the lymph nodes in the groin become swollen, hard, and painful. These are known as buboes and may eventually rupture through the skin.

In men, the sores are often found on the foreskin or the head of the penis. In women, they may appear on the labia or at the vaginal opening, where they can sometimes be less painful or mistaken for other issues like an ingrown hair or a simple cyst.

How Does Chancroid Differ from Syphilis and Herpes?

When a patient notices a genital sore, the immediate concern is often syphilis or genital herpes. However, there are key clinical differences that a doctor will evaluate:

Chancroid vs Syphilis

Syphilis typically produces a single, painless, firm sore called a chancre. Chancroid, by contrast, is almost always painful and the sores are soft. Syphilis sores usually heal on their own without treatment (though the infection remains), whereas chancroid sores persist and can worsen.

Chancroid vs Genital Herpes

Herpes usually presents as a cluster of small vesicles (blisters) that eventually break and crust over. The pain in herpes is often preceded by a tingling or burning sensation. Chancroid ulcers are typically larger and deeper than herpes lesions and do not usually have the 'blister' stage.

Treatment and Management in the UK

The good news is that chancroid is entirely curable with the correct course of antibiotics. According to UK national guidelines for the management of sexually transmitted infections, the preferred treatments include:

  • Azithromycin: Usually administered as a single oral dose.
  • Ceftriaxone: Often given as a single injection into the muscle.
  • Ciprofloxacin: A multi-day oral course (not suitable for pregnant or breastfeeding women).

It is vital to complete the full course of any prescribed medication, even if the sores begin to heal quickly. Patients should also avoid any sexual contact until the sores have completely healed and they have been cleared by a healthcare professional. Furthermore, it is essential to notify any recent sexual partners so they can be tested and treated, preventing further transmission within the community.

When to Speak to a GP Online

If you discover a new lump, bump, or sore in your genital area, it is important to seek medical advice promptly. Many people feel embarrassed discussing sexual health, but a confidential online GP consultation provides a discreet way to address your concerns from the comfort of home.

You should speak to an online doctor if:

  • You have a painful sore or ulcer on your genitals or around the anus.
  • You have noticed painful swelling in your groin.
  • You have recently had unprotected sex with a new partner or someone who has travelled recently.
  • You are concerned that symptoms of a previous STI have returned.

An online doctor can review your symptoms, provide advice on the necessary diagnostic tests, and, where appropriate, issue a prescription for treatment. They can also provide a private sick note if your symptoms or the required clinical visits interfere with your work.

Prevention and Long-term Health

Preventing chancroid follows the same principles as other STIs. The consistent and correct use of condoms significantly reduces the risk of transmission, although they may not cover all affected skin areas. Regular sexual health screenings are recommended for anyone with multiple partners or those starting a new relationship.

Untreated chancroid is known to increase the risk of HIV transmission, as the open sores provide an easy entry point for other viruses. Therefore, early diagnosis is not just about comfort; it is a critical component of long-term sexual health and safety.

Red flags — when to seek urgent help

Call 999 or go to A&E if you experience any of the following:

  • Severe, spreading infection in the groin area with high fever
  • Inability to pass urine due to extreme pain or swelling
  • Signs of systemic sepsis, such as confusion or rapid heart rate
  • Sudden, severe pelvic pain combined with a high temperature

Frequently asked questions

Common questions UK patients ask about chancroid.

How an online doctor can help

This article is for general information only and does not replace personal medical advice from a qualified doctor. Content is reviewed against UK NHS and NICE guidance by the OnlineDoctor24 editorial team and is not authored by a medical doctor. If your symptoms worsen or you are unsure, please book a consultation with a GMC-registered GP.

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