Travel Health

Altitude Sickness: UK Online Doctor Prevention with Acetazolamide

6 min readLast reviewed 24 April 2026

Educational information — not medical advice.

This article was prepared by the OnlineDoctor24 editorial team and reviewed for factual accuracy against UK clinical guidance (NHS and NICE). It is not written by a doctor and does not replace personal medical advice. For symptoms specific to you, book an online doctor consultation.

Key points

  • Altitude sickness can affect anyone above 2,500m.
  • Slow ascent ('climb high, sleep low') is the best prevention.
  • Acetazolamide (Diamox) reduces risk and severity.
  • Severe symptoms (HACE, HAPE) are life-threatening — descend immediately.

What is AMS?

Acute mountain sickness causes headache, nausea, fatigue and poor sleep — usually starting 6–24 hours after rapid ascent.

Prevention

  • Ascend gradually above 2,500m — no more than 300–500m sleeping altitude gain per day.
  • Rest day every 1,000m.
  • Hydrate well.
  • Avoid alcohol/sedatives early.
  • Acetazolamide 125–250mg twice daily, starting 1 day before ascent.

Treatment

  • Mild AMS: rest, hydrate, paracetamol, anti-emetic, acetazolamide.
  • Don't ascend further until symptoms resolve.
  • Severe (HACE/HAPE): descend immediately, oxygen, dexamethasone (HACE), nifedipine (HAPE).

Online consultation

A UK online GP can prescribe Diamox and dexamethasone for trek/expedition use after a brief consultation.

Red flags — when to seek urgent help

Call 999 or go to A&E if you experience any of the following:

  • Confusion, ataxia (HACE)
  • Severe breathlessness at rest, frothy sputum (HAPE)
  • Symptoms not improving despite stopping ascent

Frequently asked questions

Common questions UK patients ask about altitude sickness.

How an online doctor can help

This article is for general information only and does not replace personal medical advice from a qualified doctor. Content is reviewed against UK NHS and NICE guidance by the OnlineDoctor24 editorial team and is not authored by a medical doctor. If your symptoms worsen or you are unsure, please book a consultation with a GMC-registered GP.

See a UK GP about this today

Same-day video or phone consultations with GMC-registered GPs. Prescriptions, sick notes and referrals when clinically appropriate.